3-Pyridinecarboxylic acid, 5-amino-6-methyl-, ethyl ester
ethyl 5-amino-6-methylnicotinate
CAS: 1008138-73-5
Molecular Formula: C9H12N2O2
3-Pyridinecarboxylic acid, 5-amino-6-methyl-, ethyl ester - Names and Identifiers
3-Pyridinecarboxylic acid, 5-amino-6-methyl-, ethyl ester - Physico-chemical Properties
| Molecular Formula | C9H12N2O2 |
| Molar Mass | 180.2 |
| Density | 1.158±0.06 g/cm3(Predicted) |
| Boling Point | 327.9±37.0 °C(Predicted) |
| pKa | 4.95±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
3-Pyridinecarboxylic acid, 5-amino-6-methyl-, ethyl ester - Introduction
5-Amino -6-methyl-nicotinic acid ethyl ester is an organic compound with the chemical formula C8H12N2O2. The following is a description of its nature, use, formulation and safety information:
Nature:
5-Amino -6-methyl-nicotinic acid ethyl ester is a colorless to slightly yellow solid with a faint ammonia odor. It is soluble in water and many organic solvents, such as ethanol and chloroform. It is stable under acidic conditions but undergoes hydrolysis under strongly basic conditions.
Use:
5-amino -6-methyl-nicotinic acid ethyl ester is commonly used as pharmaceutical intermediates and biological dyes synthetic raw materials. It is used in the medical field to synthesize drugs for the treatment of hypertension, such as esomidine and losartan. In addition, it can also be used as a raw material for the synthesis of acid dyes for the dyes, coatings and plastics industries.
Preparation Method:
5-Amino -6-methyl-nicotinic acid ethyl ester can be obtained by reacting n-propylamine with methyl ethyl nicotinate under acidic conditions. Specific synthetic methods can refer to organic synthetic chemistry handbook or professional literature.
Safety Information:
When using and handling 5-amino -6-methyl-nicotinic acid ethyl ester, it is necessary to strictly follow laboratory safety procedures. It may be irritating to the eyes, skin and respiratory tract, so care should be taken to avoid contact. Appropriate protective gloves, glasses and masks should be worn during handling. If inhaled or exposed to the compound, immediately rinse the affected area with clean water and seek medical attention. During storage and transportation, it should be kept in a dry, cool and well-ventilated place, away from fire and combustibles.
Nature:
5-Amino -6-methyl-nicotinic acid ethyl ester is a colorless to slightly yellow solid with a faint ammonia odor. It is soluble in water and many organic solvents, such as ethanol and chloroform. It is stable under acidic conditions but undergoes hydrolysis under strongly basic conditions.
Use:
5-amino -6-methyl-nicotinic acid ethyl ester is commonly used as pharmaceutical intermediates and biological dyes synthetic raw materials. It is used in the medical field to synthesize drugs for the treatment of hypertension, such as esomidine and losartan. In addition, it can also be used as a raw material for the synthesis of acid dyes for the dyes, coatings and plastics industries.
Preparation Method:
5-Amino -6-methyl-nicotinic acid ethyl ester can be obtained by reacting n-propylamine with methyl ethyl nicotinate under acidic conditions. Specific synthetic methods can refer to organic synthetic chemistry handbook or professional literature.
Safety Information:
When using and handling 5-amino -6-methyl-nicotinic acid ethyl ester, it is necessary to strictly follow laboratory safety procedures. It may be irritating to the eyes, skin and respiratory tract, so care should be taken to avoid contact. Appropriate protective gloves, glasses and masks should be worn during handling. If inhaled or exposed to the compound, immediately rinse the affected area with clean water and seek medical attention. During storage and transportation, it should be kept in a dry, cool and well-ventilated place, away from fire and combustibles.
Last Update：2024-04-09 20:52:54
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Product Name: 5-aMino-6-Methyl-3-Pyridinecarboxylic acid ethyl ester Visit Supplier Webpage Request for quotation
CAS: 1008138-73-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1008138-73-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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